Researchers uncover a chain of molecular events behind early brain changes in Alzheimer’s
For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer’s…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
Alcohol impacts gene expression differently across brain regions
Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression…
New neural organoid system improves scalability and reproducibility for research
Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields. These include exploring the responses of brain tissue to drugs,…
Diverse biobank study links genetics to disease risk and treatment
A new study by UCLA Health published in Cell presents a major advancement in the future of personalized…
New AI system maps gene expression across the whole body
Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Study finds addiction risk tied to reward and impulse genes
Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how…
Selfish chromosomes hijack Overdrive gene to eliminate rival sperm
A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how “selfish chromosomes” cheat…
Gene mutation that aids high-altitude survival could repair myelin sheath damage
A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing…
Scientists uncover unexpected cancer target on tumor cell surfaces
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it…