Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Intensive mind-body retreat rapidly alters brain function and blood biology
Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques,…
Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections
Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new…
Study identifies molecular brake that controls overactive killer T cells
“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
Large-scale foundation model reconstructs how cells interact within tissues
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation…
45,000-Year-Old Crimean Neanderthal Reveals Long-Distance Connections across Eurasia
The Crimean Peninsula in Ukraine contains key Middle to Upper Paleolithic transitional archaeological sites, including the site of…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis
A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels…
New genetic marker may improve the ability to predict life-threatening reactions to gout medication
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication…