Scientists map the genetic control system behind FOXP3 in immune cells
The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer,…
AI chat box helps investigate complex biology in English language
Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single…
TAU researchers develop groundbreaking gene therapy to treat hearing, balance disabilities
“These findings highlight the potential of self-complementary AAVs to reduce dose requirements, minimize toxicity, and broaden clinical use…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Inflammation identified as a key driver in the earliest stages of lung cancer
By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
Large-scale foundation model reconstructs how cells interact within tissues
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Research identifies biomarkers in blood to fine-tune breast cancer interventions
Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells…