APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
New study reveals CRISPR enzyme that responds to human DNA methylation
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a…
Proteomics and AI bring earlier risk prediction into sharper focus
From Alzheimer’s risk to cardiovascular prediction, this review shows how protein profiling and AI could help detect disease…
Key gene variants tied to developmental dysplasia of the hip and osteoarthritis
Developmental dysplasia of the hip (DDH) is a polygenetic disorder that increases the risk of hip osteoarthritis. A…
High-resolution study maps molecular differences across six human cortical regions
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
Scientists link poor sleep to decreased chemotherapy response via the gut
Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have…
New research reveals how bacteria “selflessly” share DNA through GTAs
Research has shed important new light on the enemies-turned-allies that allow bacteria to exchange genes, including those linked to antimicrobial resistance (AMR). …
Migraine genes linked to worse headaches after concussion in children
A University of Calgary-led study has found evidence that children with genes predisposing to migraine might have an…
New research reveals how parasites break out of host cells
Parasites are a major global health problem, underlying many human diseases worldwide. For example, Plasmodium falciparum, the parasite…
Brain organoids reveal mutation-specific insights for Rett syndrome
Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of…
Vibrio cholerae acquires antiviral defenses through horizontal gene transfer
Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with antiviral…
Study explains why current BET inhibitors fail in cancer treatment
For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with…