Micro-RNA in sperm proves vital for human embryogenesis
The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University,…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden…
How diet affects aging metabolism differently for men and women
Researchers have uncovered striking sex-based differences in how diet influences metabolism with age, revealing that plant proteins and…
Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections
Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new…
Researchers use genetic engineering to create “product-ready” snakebite antivenom
An international team of researchers has used genetic engineering to create the first ever “product-ready” antivenom for snakes…
Kids First DRC releases 37th pediatric study on rare childhood cancers
The Gabriella Miller Kids First Data Resource Center (Kids First DRC) has released its 37th pediatric research study,…
Scientists create detailed single-cell map of the developing human brain
Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…