Timing of genetic mutation dictates childhood leukemia aggressiveness
A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with…
Bacterial enzyme linked to heart complications in pneumonia
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Scientists Sequence Genome of Vampire Squid
The genome of the vampire squid (Vampyroteuthis sp.) is one of the largest animal genomes, exceeding 10 billion…
Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Landmark Japanese genome cohort reveals best practices for managing massive DNA databases
At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo)…
Researchers Using Neanderthal DNA to Learn More About How Human Faces Develop and Evolve
University of Edinburgh scientist Hannah Long and colleagues show how a region of Neanderthal DNA is better at…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Exploring endogenous retroviruses as hidden drivers of alcohol use disorder
Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1…