Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Landmark Japanese genome cohort reveals best practices for managing massive DNA databases
At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo)…
Researchers Using Neanderthal DNA to Learn More About How Human Faces Develop and Evolve
University of Edinburgh scientist Hannah Long and colleagues show how a region of Neanderthal DNA is better at…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Exploring endogenous retroviruses as hidden drivers of alcohol use disorder
Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
45,000-Year-Old Crimean Neanderthal Reveals Long-Distance Connections across Eurasia
The Crimean Peninsula in Ukraine contains key Middle to Upper Paleolithic transitional archaeological sites, including the site of…
Immune cell dysregulation and inflammatory mediators shape epilepsy risk
Background and objectives Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…