New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Landmark Japanese genome cohort reveals best practices for managing massive DNA databases
At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo)…
Scientists map the genetic control system behind FOXP3 in immune cells
The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer,…
Single-cell study reveals how HPV shapes immune landscape in penile cancer
Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with…
The caffeine conundrum in rapid depression treatments
Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic…
Blood protein pattern linked to increased risk of hereditary atherosclerosis
A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is…
Study finds more commonalities between CTE and Alzheimer’s disease at the genetic level
Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share…
Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease
A global research team has pinpointed the enzyme fueling hydrogen production in healthy guts and shown how its…