New prime assembly method enables long and precise DNA insertions
Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene…
Study identifies DNA loops as essential for tissue regeneration
After an injury, DNA not only alters its activity but also the way it is organized spatially within…
Blood protein profiling could improve rare disease diagnosis
Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England…
Paternal sperm epigenetics may help explain early pregnancy loss
When a pregnancy ends early and unexplained, the search for answers usually begins with the mother. Lacey Luense,…
Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
New human genome benchmark captures both parental copies with near-perfect accuracy
By capturing both inherited chromosome sets and reaching genomic regions missed by conventional benchmarks, T2T-HG002 could help shift…
Cells share universal on switches but evolve unique strategy to silence genes
The signals that cells use to switch genes on have remained almost unchanged across two billion years of…
Intensive poultry farming and campylobacter evolution
Genomic analyses reveal that the rise of industrial poultry farming has transformed the ecology and evolution of Campylobacter…
New computational technique traces ghost ancestry in modern human genomes
UC Berkeley researchers have identified regions of DNA that humans inherited from two unknown ancestors as a result…
Taste preference genes drive overeating and metabolic disease risk
Ever wonder why some people crave sweets while others can take them or leave them? Preliminary findings from…
Taiwan Biobank data reveals ongoing natural selection in living humans
For more than a century, scientists have sought to reconstruct human evolution using diverse lines of evidence, including…
RNA-based testing can improve detection of key lung cancer biomarkers
New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations…