New research explains how embryos establish germline cell boundaries
Every embryo of an organism that reproduces sexually faces an early and consequential decision: which of its cell…
Cells detect and silence invading transposons through abnormal RNA signals
Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell…
How cost, access, and awareness barriers are slowing BRCA testing
Despite broader guidelines and life-saving targeted therapies, real-world evidence reveals persistent gaps and inequities in BRCA testing, raising…
Online tool helps cancer patients share genetic risk with families
When a person with cancer finds out they carry an inherited genetic variant that puts them at higher…
Selfish chromosomes hijack Overdrive gene to eliminate rival sperm
A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how “selfish chromosomes” cheat…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
Trial aims to improve family communication about inherited colorectal cancer risk
In time for Colorectal Cancer Awareness Month in March, the Alliance for Clinical Trials in Oncology has launched…
Single prenatal exposure to fungicide linked to disease across 20 generations
A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent…
Why lung cancer in never smokers is rising and how targeted detection could reduce deaths
Researchers reveal why lung cancer in people who never smoked is increasing and explore how genetics, environmental exposures,…
Lysosomal activity in worms linked to transgenerational extension of lifespan
In the Wang Lab, it’s not unusual for worms to live for a long time. HHMI Janelia Research…