MXene-based hydrogel offers dual-action treatment for periodontitis
Periodontitis is a highly prevalent chronic inflammatory disease worldwide. It leads to periodontal tissue destruction, alveolar bone resorption,…
Exhausted T cells balance graft tolerance and infection risk
A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this…
Statins may trigger muscle side effects by activating inflammatory danger signals
New experimental findings reveal how statins may push vulnerable muscle cells into a stress state, suggesting future strategies…
Study reveals dual role of PFK enzyme in metabolism and cell cycle progression
A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA…
Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis
Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury. Chondrocytes, the sole…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer
Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide…