Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar Reetz MT, Wu…
Genomics will forever reshape forensic science and criminal justice | Genome Biology
Historically, genomics and forensic science have progressed along distinct trajectories. Genomics, driven by large-scale initiatives like the Human…
Regulation of heterosis-associated gene expression complementation in maize hybrids | Genome Biology
Plant genetic resources The IBM-RIL syn. 4 population [19] represents a collection of highly diversified genotypes with respect…
Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa | Genome Biology
Barceló C, Labarta A. Archivos moriscos: textos árabes de la minorÃa islámica valenciana 1401–1608. Universitat de València; 2009.…
Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects
Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes
Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands Camiel M. van der Laan, Hill F. Ip, Jouke-Jan Hottenga, René…
Is enhancer-driven gene regulation all wrapped up?
Symmons, O. et al. The Shh topological domain facilitates the action of remote enhancers by reducing the effects…
Regulatory genome annotation | Nature Reviews Genetics
Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91–100…
Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs
Identifying the structures of autism phenotypes To best reflect the complexity of presentations across autistic individuals, we identified…
The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease
School of Computation, Information and Technology, Technical University of Munich, Garching, Germany Vicente A. Yépez, Rebeka Luknárová, Felix Brechtmann, Leon Kraß, Shubhankar…
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling
Fogg, C. et al. The dynamics of frailty development and progression in older adults in primary care in…
A genome-wide association analysis reveals new pathogenic pathways in gout
Kuo, C. F. et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11,…