Bioresorbable Sensor Tracks Deep-Tissue Lactate for Over 10 Days in Animals
Researchers developed a fully bioresorbable sensor that continuously tracked deep-tissue lactate for more than 10 days in animal…
Targeting CMPK2-intervened redox metabolism to mitigate hepatic ischemia-reperfusion injury
HIRI is a major clinical challenge that occurs when blood supply to the liver is temporarily interrupted and…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
Sleep apnea and erectile dysfunction share a stronger link than expected
A new meta-analysis suggests that worsening sleep-disordered breathing may track with declining erectile function, highlighting why men with…
New Framework Aims to Transform High-Altitude Medicine Through Whole-Body Approach to Hypoxia
Figure 1. Conceptual framework of Hypoxia Stress-induced Multi-organ Injury (HSMI). Figure 2. Future directions for advancing high-altitude medicine…
Photodynamic strategies enhance antibacterial performance of titanium orthopedic implants
1. Background The increasing global aging population has led to a steady rise in the demand for titanium…
Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
Novel microneedle patch accelerates healing of chronic diabetic wounds using light
Researchers from Nanjing Drum Tower Hospital, Southeast University, and Wenzhou Medical University have developed a novel microneedle patch…
Researchers show red blood cells drive better glucose tolerance at high altitude
New research reveals how hypoxia-driven red blood cell adaptations may reshape glucose regulation, offering fresh insight into diabetes…
Low oxygen turns red blood cells into powerful glucose sinks
Scientists have long known that people living at high altitudes, where oxygen levels are low, have lower rates…
Hypoxia rewires red blood cells to clear excess glucose
In a 2023 paper on hypoxia and glucose metabolism, our lab showed how organisms rewire their metabolism to…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…