Blood-based biomarkers and the new landscape of Alzheimer’s research
For much of the past century, Alzheimer’s disease has been one of medicine’s most daunting frontiers – biologically…
Using sound waves to soften tumors and boost chemotherapy
Cancer is one of the leading causes of death in the U.S., second only to heart disease. But…
Virus shells use asymmetry to control RNA release and infection
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new…
Tianjin grading system improves prognosis prediction in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools.…
Bioluminescent tool illuminates single-cell activity in living brains
A decade ago, a group of scientists had the literally brilliant idea to use bioluminescent light to visualize…
Researchers map how brain networks differ in individuals at high clinical risk for psychosis
Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and NHG Health’s…
SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection
Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide. When the eustachian tube-responsible…
Fullerenes offer a simpler path to creating high-sensitivity MRI targets
Magnetic resonance imaging (MRI) is invaluable in the medical world. But despite all the good it does, there…
New technique overcomes technological barrier in 3D brain imaging
Scientists at the Swiss Light Source SLS have succeeded in mapping a piece of brain tissue in 3D…
New technique helps understand how bacterial shapes contribute to disease
Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Breakthrough platform reveals the choreography of mammalian transcription
Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads…