New genetic marker may improve the ability to predict life-threatening reactions to gout medication
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication…
Hypoxia weakens the body’s infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Epigenetic editing enables safer and more effective T cell therapies
Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
How The Shutdown Impacts Healthcare
In this week’s edition of InnovationRx, we look at the shutdown’s impact on healthcare, the Nobel Prize winners…
Early antiviral treatment following gammaherpesvirus-68 infection of the central nervous system prevents subsequent multiple sclerosis-like disease | Journal of Neuroinflammation
Dendrou CA, Fugger L, Friese MA. Immunopathology of multiple sclerosis. Nat Rev Immunol. 2015;15(9):545–58. CAS PubMed Google Scholar …
Researchers discover how HIV hides in different parts of the body
Researchers at Western University and the University of Calgary have discovered how HIV hides in different parts of…
World’s first vaccine trial against elephant endotheliotropic herpesvirus proves safe and effective
The world’s first vaccine trial against elephant endotheliotropic herpesvirus (EEHV) – a leading cause of death in young…
Study identifies PTX-3 as potential marker for long COVID and tissue damage
A research team working at MedUni Vienna has demonstrated that a specific component of the immune system (PTX-3)…
Boosting the immune system to prevent cancer recurrence and improve survival
In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children’s Hospital…
Understanding how lipids activate LC3-associated phagocytosis
LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a…