Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Immune scaffold predicts onset weeks early
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Novel treatment disrupts tumor immunosuppression in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%. University…