Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Engineered Salmonella therapy delivers immune payloads to combat cancer
A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled “ACTM-838, a novel systemically delivered…
Engineered CAR T cells show promise against solid tumors
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…
Radiomics significantly outperforms clinical models for predicting NPC treatment outcome
Nasopharyngeal carcinoma (NPC) is a highly aggressive malignancy, with most patients presenting at locally advanced stages. While immune…
Novel treatment disrupts tumor immunosuppression in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%. University…
New findings show lymph nodes educate T cells to combat disease
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the…
Scientists Find a Way to “Bulletproof” T Cells Against Cancer
Researchers at the University of Pittsburgh have discovered that the harsh environment inside tumors, characterized by low oxygen…
Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests
Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest…
A single genetic mutation may have made humans more vulnerable to cancer than chimpanzees
(SACRAMENTO) New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why…