Novel mRNA-based therapy may offer a new path to tackle antibiotic-resistant infections
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have reported early success with a…
Single-cell study reveals how HPV shapes immune landscape in penile cancer
Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Targeting myeloid cells to enhance cancer immunotherapy
Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Engineered Salmonella therapy delivers immune payloads to combat cancer
A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled “ACTM-838, a novel systemically delivered…
Engineered CAR T cells show promise against solid tumors
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…