Protein MIIP suppresses colorectal cancer by regulating immune cell signaling
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Defining the limits of immunotherapy in early small-cell lung cancer
Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer…
Study finds cockroach allergy often driven by shared proteins across arthropods
A new molecular analysis reveals that many patients labeled as cockroach-allergic may actually be reacting to shared proteins…
Microbial ecosystems influence success of cancer checkpoint immunotherapy
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.…
Dual targeting strategy may improve treatment for resistant lung cancers
Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G.…
Novel antibody blocks Epstein-Barr virus, curing follicular lymphoma — and a plan to reduce cancer in Washington state
SEATTLE – March 4, 2026 – Below are summaries of recent Fred Hutch Cancer Center research findings, patient…
Dr. Soheil Meshinchi, a leading expert in acute myeloid leukemia, named Dylan Burke Endowed Chair in Immunotherapy
As a child, Dylan Burke was an athlete and gymnast who shunned sugar and worked out every day, and a budding mad…
Combination therapy may help overcome barrier in early-stage prostate cancer treatment
A multi-institutional study led by Mayo Clinic and published in Cell Reports Medicine reports that pairing a next-generation immunotherapy with standard hormone therapy…
Remote-controlled CAR T cells offer safer cancer therapy
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…