Researchers develop method to generate billions of cDC1 immune cells
Conventional type 1 dendritic cells, known as cDC1 cells, are immune cells that help initiate responses against intracellular…
Researchers uncover molecular pathway controlling bone resorption and tooth eruption
RUNX2 is best known as a master transcription factor of osteoblast differentiation. Mutations in, or haploinsufficiency of RUNX2…
Novel gene rejuvenation therapy preserves cell identity while reversing age
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified “hallmarks…
Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
Bioresorbable Sensor Tracks Deep-Tissue Lactate for Over 10 Days in Animals
Researchers developed a fully bioresorbable sensor that continuously tracked deep-tissue lactate for more than 10 days in animal…
Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
Single DNA injection provides long-lasting weight loss in mouse study
Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic…
Gene therapy successfully treats deadly childhood liver disease in mice
A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that…
Gut microbes control liver genes by flipping DNA switches
A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered…
Kyoto University identifies key regulator of insulin production
A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas…
Identifying the ages when Alzheimer’s biomarkers sharply change
New research pinpoints the ages when Alzheimer’s-related brain changes accelerate, offering critical clues to when screening may be…