Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
Bioresorbable Sensor Tracks Deep-Tissue Lactate for Over 10 Days in Animals
Researchers developed a fully bioresorbable sensor that continuously tracked deep-tissue lactate for more than 10 days in animal…
Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
Single DNA injection provides long-lasting weight loss in mouse study
Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic…
Gene therapy successfully treats deadly childhood liver disease in mice
A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that…
Gut microbes control liver genes by flipping DNA switches
A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered…
Kyoto University identifies key regulator of insulin production
A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas…
Identifying the ages when Alzheimer’s biomarkers sharply change
New research pinpoints the ages when Alzheimer’s-related brain changes accelerate, offering critical clues to when screening may be…
New research reveals how parasites break out of host cells
Parasites are a major global health problem, underlying many human diseases worldwide. For example, Plasmodium falciparum, the parasite…
Targeting senescent fat cells provides new hope for ovarian cancer
Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms…
Nanomedicine offers targeted solutions for breast cancer treatment
Breast cancer (BCA) is one of the most common cancers worldwide, with high mortality and morbidity in women.…