Targeted antibody therapy provides long-lasting relief from neuropathic pain
Pain is a natural protective mechanism that alerts the body to actual or potential injury. But when nerves…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Scientists discover molecular mechanism behind anesthesia-induced unconsciousness
Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used…
Amsterdam UMC researchers overturn long-standing biological pacemaker dogma
Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. In a new preclinical…
Researchers identify genetic cause of severe childhood lung disease
A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in…
The molecular mechanism that turns cool temps into nerve signals
When you reach into a bucket of ice, open your front door on a snowy day, or feel…
New review reveals complex polygenic architecture underlying common epilepsies
An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common…
Ion channel TRPV4 found to regulate relief after scratching an itch
When you scratch an itch, something tells your brain when to stop. That moment of relief, when scratching…
A pill that confirms you actually swallowed your medicine
By using a temporary Faraday-cage coating that dissolves in minutes, the SAFARI capsule delivers highly specific proof of…
Scientists identify a molecular switch that controls water flow in the gut
Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how…
Study reveals how Ebola and Marburg viruses damage the human gut
Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by…
Groundbreaking mouse cortex model opens new frontiers in neuroscience
Harnessing the muscle of one of the world’s fastest supercomputers, researchers have built one of the largest and…