Study reveals how CaMKIIα proteins organize during memory formation
Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University, Kyoto University, SOKENDAI, and the National Institute…
Cell proliferation gene plays a distinct role in cells that no longer proliferate
In a tale of identities as divergent as “The Prince and the Pauper,” a well-known cancer-causing gene also…
Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes
From mitochondrial fragmentation to antioxidant defenses, researchers reveal how the same viruses can drive cellular damage in vertebrates…
New protein blueprint opens door for targeted Parkinson’s disease therapies
Researchers at Weill Cornell Medicine have uncovered how a key Parkinson’s protein called LRRK2 shifts between inactive and…
Scientists unlock molecular structure of key protein linked to cancer, neurological diseases
After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ),…
Scientists uncover new molecular mechanism driving gastrointestinal stromal tumors
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations driving…
New study uncovers how prostate cancer cells evade treatment
Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways…
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
Bee-derived propolis shows potent antiviral activity against varicella-zoster virus
Announcing a new article publication for Zoonoses journal. Varicella-zoster virus (VZV) is a clinically important human neurotropic herpesvirus…
Pim1 identified as promising therapeutic target for inflammatory arthritis treatment
The research team led by Professor Zhongyu Xie from Sun Yat-sen University revealed a new mechanism by which…
Fred Hutch study dramatically expands therapeutic range of approved kinase drugs
Casting a wide net To find out what a drug can do beyond what it is designed to…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…