LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
Researchers uncover hidden mechanism behind cancer-linked SPOP mutations
Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap,…