Natural hormone activates brain-to-liver signaling pathway to suppress liver inflammation
Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight…
Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma
Background and aims The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent…
Exhausted T cells balance graft tolerance and infection risk
A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this…
Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth
Digestion is hard on the cells that line the human gut, and they are constantly being shed and…
244-Million-Year-Old Fossil Preserves Earliest Reptilian Digestive System
An exquisitely preserved specimen of Austronaga minuta, a small, long-necked marine reptile from the Triassic of China, contains…
Daily tomatoes lowered a key marker of liver fat in MASLD trial
A six-week tomato-rich diet outperformed a tomato-free diet on an important marker of hepatic steatosis, pointing to a…
Traditional Japanese medicine for obesity may help reduce age-related tissue fibrosis
A traditional Japanese medicine used for obesity may do more than support weight loss. Researchers at the University…
AI-powered blood test detects liver cancer across distinct populations
Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer…
Review outlines effective approaches to reduce recurrent hepatic encephalopathy
Hepatic encephalopathy (HE) is a neurologic complication of advanced liver disease, causing impaired functioning, reduced quality of life…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…
Novel interventional approach successfully treats rare hepatic myelopathy
Hepatic myelopathy (HM) is a rare neurological complication of decompensated chronic liver disease that profoundly impairs quality of…
A common dietary nutrient feeds a gut pathway linked to atrial fibrillation
A 5,090-person cohort and complementary mouse experiments trace how a diet-linked microbial pathway could reshape atrial structure, electrical…