Engineered Listeria boosts innate immunity against cancer
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Environmental Factor – December 2025: Macrophages represent an untapped target for new medicines
Macrophages — the immune cells best known for defending the body against infections — may also hold the…
Discovery of unexpected mechanism may help improve healing across muscle injuries
At the cellular level, the mechanics of how muscle tissue repair occurs gets complicated. There are significant differences…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Targeting myeloid cells to enhance cancer immunotherapy
Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard…