Macrophage

Discovery of unexpected mechanism may help improve healing across muscle injuries

April 21, 2026

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…

HHealth

SLIT2 protein levels in the eye and blood linked to cognitive function

March 16, 2026

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited…

SScience

March 13, 2026

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to…

HHealth

Regular mammograms linked to longer survival in women over 80

March 11, 2026

An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time…

SScience

March 7, 2026

Recently, teams led by Prof. Yiming Zhang from Xinqiao Hospital, Army Medical University,Prof. Fazhi Qi from Zhongshan Hospital,…

HHealth

Research uncovers alternative inflammatory pathway in rheumatoid arthritis treatment

February 28, 2026

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four…

HHealth

Unlocking the secrets of oral bacteria to fight tooth decay

February 14, 2026

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…

SScience

January 22, 2026

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…

HHealth

Environmental Factor - December 2025: Macrophages represent an untapped target for new medicines

December 1, 2025

Macrophages — the immune cells best known for defending the body against infections — may also hold the…

HHealth

November 22, 2025

At the cellular level, the mechanics of how muscle tissue repair occurs gets complicated. There are significant differences…

TTechnology

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

November 4, 2025

Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…

HHealth

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

November 1, 2025

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…

Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

Protein MIIP suppresses colorectal cancer by regulating immune cell signaling

Pen-strep treatment rewires mechanical sensing in immune cells

Dual-positive hybrid cells linked to shorter survival in advanced breast cancer

TREM2 helps macrophages survive and repair radiation damaged skin

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

Engineered Listeria boosts innate immunity against cancer

Study shows DHPS enzyme controls macrophage maturation across multiple organs

Environmental Factor – December 2025: Macrophages represent an untapped target for new medicines

Discovery of unexpected mechanism may help improve healing across muscle injuries

Northwestern team develops antibody to expose hidden pancreatic cancer cells

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers