Targeting ANO6 protein weakens pancreatic cancer and boosts immunity
Fox Chase Cancer Center researchers identified a potential therapeutic target for pancreatic cancer after showing that tumor growth…
Gene therapy and special goggles help some blind adults detect objects again
Scientists are testing whether surviving retinal nerve cells, a light-sensitive protein, and specially designed goggles could offer a…
Tiny archaeon offers new clues to the minimum genetic requirements for life
Scientists have discovered a previously unknown microorganism, which has the smallest genome ever found, that is possibly able…
New study explains how TMEM63B protein regulates cell membranes
An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its inactive…
Toxoplasma remodels host cell surfaces to trigger invasion
Before the parasite Toxoplasma gondii can invade a cell, it has to know it has reached the right place. New…
Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide
A computational search of cobra cardiotoxins put 14 venom-inspired peptides through structural, antibacterial, and toxicity testing, providing a…
Study reveals structure of color-sensing cone cells in primates
For over 60 years, scientists have debated a basic structural question about cone photoreceptors, the cells that let…
Scientists capture how bacteria build their protective antibiotic-resistant barriers
Gram-negative bacteria are responsible for causing several infections that are hard to treat, owing to their high resistance…
Engineered immune cells help eliminate severe bacterial infections effectively
Severe bacterial infections remain a major global health challenge because antibiotics alone often fail when the host immune…
Bacterial extracellular vesicles show potential for cancer diagnosis and treatment
Bacteria shed membrane-enclosed tiny particles filled with proteins, lipids, DNA, RNA and metabolites. These particles, commonly known as…
Study sheds new light on the physiological roles of protein quality control at the ribosome
Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research…
Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes
From mitochondrial fragmentation to antioxidant defenses, researchers reveal how the same viruses can drive cellular damage in vertebrates…