New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
Vitamin B2 metabolism helps cancer cells resist ferroptosis
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Real-world study shows modest weight regain after GLP-1 discontinuation
As the use of injectable GLP-1 drugs continues to rise, questions persist about what happens after patients stop…
Low-protein diet activates mice gut microbes to make fatty tissue burn energy
Researchers have discovered that specific gut bacteria work together with diet to “flip a metabolic switch” — transforming…
How N-Acylethanolamines Control Appetite, Energy Balance, and Metabolic Health
IntroductionWhat are NAEs?NAEs in metabolic healthNAEs and cognitionTherapeutic and lifestyle implicationsChallenges and future directionsConclusionsReferences Further reading From appetite control…
Eating earlier in the day is linked to lower nighttime glucose in gestational diabetes
Starting the day’s first meal earlier may shift the body’s daily glucose rhythm and reduce overnight glucose levels…
Scientists simulate complete life cycle of a minimal bacterial cell
By simulating the life cycle of a minimal bacterial cell – from DNA replication to protein translation to…
Microbial ecosystems influence success of cancer checkpoint immunotherapy
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.…
Struggling with slow metabolism? Doctors reveal 8 everyday foods that can naturally boost digestion and burn more calories
Dr Manjusha Agarwal, Senior Consultant Internal Medicine at Gleneagles Hospital, Parel, explains the importance of maintaining metabolic balance.…
Dual targeting strategy may improve treatment for resistant lung cancers
Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G.…
Researchers propose that Parkinson’s disease may start in the gut, not the brain
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal…