Vitamin A derivative prevents immune cell exhaustion in brain tumors
Immune cells can become exhausted after prolonged exposure to cancer, gradually losing their ability to attack tumor cells.…
Biotherapeutic metabolite repairs gut damage caused by HIV infection
Researchers at the UC Davis School of Medicine have identified a naturally occurring metabolite that repairs gut damage caused by…
Blood metabolism maps how lifestyle tracks function in cognitive aging
A new pathway-level analysis links diet and physical activity to blood metabolic patterns associated with mobility, cognition, independence,…
Gut microbes emerge as potential players in estrogen-driven cancers
Scientists say gut microbes may do more than recycle estrogen, but turning the endocrine-microbiome axis into a cancer…
Targeting lipid enzymes triggers starvation states in aggressive tumor cells
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for…
Glucose acts as a metabolic signal for myelin development
Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have uncovered a surprising…
Study identifies new genetic pathways driving cardiometabolic disease risk
A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease,…
L-arginine stabilizes protein droplets and prevents harmful fibril formation
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients
A clinical study suggests metformin may reproduce part of exercise’s metabolic signature in prostate cancer patients, raising Lac-Phe…
Metformin mimics exercise-related metabolic effects in prostate cancer patients
A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise’s core…
Fiber supplement stabilizes blood sugar in gestational diabetes
A simple fiber supplement could reshape the gut microbiome, stabilize blood sugar spikes, and even prevent preterm births…
Optimization of CAR T cells to destroy solid tumors
A team led by LMU physician Sebastian Kobold has found a way to allow the body’s immune system…