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Browsing Tag

Metabolites

29 posts
HHealth
New technology embeds unique genetic identifiers in engineered cells
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Study identifies new genetic pathways driving cardiometabolic disease risk

  • April 24, 2026
A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease,…
HHealth
Study: Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations. Image Credit: Andrii Zastrozhnov / Shutterstock
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Parents’ intake of sugar substitutes may influence offspring gut biology, study finds

  • April 14, 2026
A new mouse study suggests that sweeteners consumed by parents may reshape gut bacteria, microbial metabolites, and metabolic…
HHealth
New study reveals a 25-year rise in alcohol-induced mortality
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Alcohol impacts gene expression differently across brain regions

  • March 31, 2026
Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression…
HHealth
Whole wheat diets may reduce the risk of inflammatory bowel disease
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Whole wheat diets may reduce the risk of inflammatory bowel disease

  • March 25, 2026
Enriching the diet with wheat fiber protects mice against intestinal inflammation, according to a study published by researchers…
HHealth
Study: Fermented foods consumption, all-cause, and cause-specific mortality: a meta-analysis of prospective cohort studies. Image Credit: sweet marshmallow / Shutterstock
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Yogurt, cheese, and chocolate consumption is tied to reduced mortality risk, researchers report

  • March 18, 2026
Could everyday foods like yogurt and chocolate quietly shape how long we live? A sweeping global analysis reveals…
HHealth
Study: Translocation of bacteria from the gut to the brain in mice. Image Credit: Corona Borealis Studio / Shutterstock
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Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

  • March 16, 2026
A new mouse study reveals that under certain dietary conditions, gut bacteria can reach the brain without entering…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Microbial ecosystems influence success of cancer checkpoint immunotherapy

  • March 9, 2026
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.…
HHealth
Environmental insults reduce gut resilience and initiate convergent mechanisms that drive Parkinson’s disease. A lifetime of environmental insults (including Western diets and food additives, nano- and microplastics, pesticides and herbicides, industrial solvents, and air pollution) act on the intestinal microbiome and barrier. These exposures promote microbiota dysbiosis, disrupt tight junctions, and erode the mucus layer, collectively reducing gut resilience. Once this peripheral defense is compromised, several mechanistic pathways propagate pathology to the brain: (a) amyloid seeding by bacterial functional amyloids, (b) maladaptive T cell education and autoimmune responses, (c) microbiome-driven metabolic shifts that generate neurotoxic metabolites and reduce short-chain fatty acids, and (d) systemic inflammatory amplification. Together, these processes lower the threshold for α-syn misfolding, neuroinflammation, and neurodegeneration.
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Researchers propose that Parkinson’s disease may start in the gut, not the brain

  • March 6, 2026
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal…
HHealth
Periodontal bacteria trigger bone density reduction via the gut
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Periodontal bacteria trigger bone density reduction via the gut

  • March 4, 2026
Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly…
SScience
Machine learning unlocks blood test secrets for spinal cord injury
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Metabolite-driven AI model accurately estimates time of death

  • February 25, 2026
Artificial intelligence can be used to provide a more precise time of death, which can be crucial in…
HHealth
Raw meat, fish, and eggs.
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Health benefits and risks uncovered

  • February 2, 2026
A new review finds that while the carnivore diet may deliver short-term improvements, weak evidence and emerging risks…
HHealth
Study: Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality. Image Credit: Kateryna Kon / Shutterstock
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How modern lifestyles reprogram the gut microbiome and shape disease risk

  • January 28, 2026
From jet lag and poor sleep to exercise and chronic stress, this review unpacks how everyday lifestyle factors…
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