Elevated CD36 drives lymph node metastasis of breast cancer by activating Hippo-YAP signaling-mediated anoikis resistance
Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers…
Bifunctional biomaterials for postoperative management of osteosarcoma
Background Osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. The current standard treatment…
Tianjin grading system improves prognosis prediction in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools.…
AI turns routine pathology slides into powerful maps of the tumor immune landscape
By transforming standard H&E slides into virtual multiplex protein maps, GigaTIME reveals how immune activity, tumor invasion, and…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
Hematological and biochemical indicators show growing value in breast cancer management
Breast cancer remains a predominant global health challenge for women, with late-stage diagnosis being a key contributor to…
Study shows one in ten young cancer patients develop metastatic recurrence
A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in…
New light-based technology arranges cellular messengers with unprecedented precision
In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots. Guided…
Local anesthetic lidocaine may mitigate pancreatic cancer metastasis
Pinned between the stomach and spine, the pancreas supervises both digestion and blood sugar in the body. It’s also the…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Ccancer cell nuclear hypertrophy can suppress metastasis
In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell’s genetic information storage) larger than…