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Browsing Tag

Microglia

19 posts
SScience
Interconnected Neurons Complex Network Brain Cells
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A Human-Specific Gene May Help Explain Our Extraordinary Brainpower

  • August 12, 2026
A human-specific gene may help explain why key brain cells mature so slowly and what that timing means…
HHealth
AI-powered deep brain stimulation improves walking in Parkinson's patients
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Brain’s immune cells play key role in maintaining stability of neuronal networks in Alzheimer’s disease

  • July 15, 2026
Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain –…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Cancer-linked mutations in the brain cells may drive Alzheimer’s disease

  • April 22, 2026
As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children’s…
HHealth
Scientists uncover how amino acids stabilize proteins in solution
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Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

  • April 8, 2026
A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually…
HHealth
Environmental insults reduce gut resilience and initiate convergent mechanisms that drive Parkinson’s disease. A lifetime of environmental insults (including Western diets and food additives, nano- and microplastics, pesticides and herbicides, industrial solvents, and air pollution) act on the intestinal microbiome and barrier. These exposures promote microbiota dysbiosis, disrupt tight junctions, and erode the mucus layer, collectively reducing gut resilience. Once this peripheral defense is compromised, several mechanistic pathways propagate pathology to the brain: (a) amyloid seeding by bacterial functional amyloids, (b) maladaptive T cell education and autoimmune responses, (c) microbiome-driven metabolic shifts that generate neurotoxic metabolites and reduce short-chain fatty acids, and (d) systemic inflammatory amplification. Together, these processes lower the threshold for α-syn misfolding, neuroinflammation, and neurodegeneration.
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Researchers propose that Parkinson’s disease may start in the gut, not the brain

  • March 6, 2026
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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Grant supports research into how microglia may spread toxic tau in Alzheimer’s

  • February 21, 2026
A researcher with the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio has…
HHealth
Cumulative social advantage linked to slower biological aging and lower inflammation
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Aging brains struggle to recycle synaptic proteins

  • February 3, 2026
As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren’t sure why. …
HHealth
Women with isolated REM sleep behavior disorder show lesser brain atrophy than men
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Regulating microglial phagocytosis through immunotherapy could slow Parkinson’s disease progression

  • February 2, 2026
By analyzing tissue from patients with Parkinson’s disease, and animal and cellular models of the disease, a research…
HHealth
Women with isolated REM sleep behavior disorder show lesser brain atrophy than men
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New atlas of brain lysosomes sheds light on neurodegenerative disorders

  • January 27, 2026
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
SScience
Discovery of unexpected mechanism may help improve healing across muscle injuries
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Study shows DHPS enzyme controls macrophage maturation across multiple organs

  • January 22, 2026
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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Suppressing brain immune cells enhances memory recall in young mice

  • January 21, 2026
Babies of every species from mouse to human rapidly forget things that happen to them-an effect called infantile…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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Blocking microglia can prevent infantile amnesia

  • January 20, 2026
Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting (“infantile amnesia”) and…
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