Itaconate and its derivatives in human health and diseases
Wu, R. et al. ACOD1 in immunometabolism and disease. Cell Mol. Immunol. 17, 822–833 (2020). Article CAS PubMed …
One Tiny Chemical Difference in RNA Could Help Explain the Origins of Life
Researchers found that RNA droplets can shift from fluid structures into more rigid, gel-like networks. That behavior could…
ESCRT-III proteins play an unexpected role in protecting DNA bridges during cell division
Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However,…
St. Jude scientists uncover regulatory mechanism for crucial developmental pathway
St. Jude Children’s Research Hospital scientists uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a pathway…
The genomic position of an enhancer modulates bursting dynamics of the cognate promoter
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
Scientists capture atomic images to improve RNA interference drug design
RNA interference is a natural mechanism for living cells to control whether specific genes are being used or…
These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs
Our genomes are full of mutations that have the potential to damage our health or even kill us.…
New study uncovers how prostate cancer cells evade treatment
Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways…
New single-protein analysis technique provides unprecedented information on scramblases
A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical…
Tiny Genetic Change Turns Female Mice Into Males, Scientists Discover
One DNA-letter change in non-coding DNA caused female mice to develop as males, revealing how regulatory DNA can…
Genetic blueprints bypass individual neuron analysis to accelerate mammalian brain research
While E. Josie Clowney would never suggest that neuroscience is simple, a new study by her team at…