Structural variation in 1,019 diverse humans based on long-read sequencing
Samples and DNA extraction We initially selected 1,064 samples from the 1kGP collection, sourcing genomic DNA from Coriell…
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair
PacBio Revio HiFiPCR-free Revio HiFi Sequencing (Dataset ID: PB-HiFi-1) Library Preparation Library preparation was performed using previously isolated…
Understanding the landscape: assistive technology and work challenges for people with disabilities in Saudi Arabia
Based on their systematic review of 41 studies examining workplace inclusion of PwDs and exploring the relationship between…
Complex genetic variation in nearly complete human genomes
Liao, W.-W. et al. A draft human pangenome reference. Nature 617, 312–324 (2023). Article ADS CAS PubMed PubMed…
AI helps assemble ‘brain’ of future quantum computer
Quantum computing qubits are arranged in a grid in this artist’s illustration.Credit: Getty Artificial intelligence (AI) tools are…
Whole-exome sequencing analysis identifies risk genes for schizophrenia
Lally, J. & MacCabe, J. H. Antipsychotic medication in schizophrenia: a review. Br. Med. Bull. 114, 169–179 (2015).…
Analog optical computer for AI inference and combinatorial optimization
Experimental set-up The key components of our experimental set-up are shown in Fig. 1a and Extended Data Fig.…
Parent-of-origin effects on complex traits in up to 236,781 individuals
UK Biobank genotype processing We used the UK Biobank Axiom Array data provided in PLINK format39 and converted…
the gene-altering tools tackling deadly disorders
Brain cells (artificially coloured) can be infected by a virus carrying the apperatus to correct disease-causing mutations. Credit:…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target
Schlame, M. & Xu, Y. The function of tafazzin, a mitochondrial phospholipid-lysophospholipid acyltransferase. J. Mol. Biol. 432, 5043–5051…
Salt-templated transformation of waste plastics into single-atom catalysts for environmental and energy applications
Universality of the synthesis in plastics-derived SACs Figure 1a illustrates the procedure of SAC synthesis from various plastics and…
Transient domain boundary drives ultrafast magnetisation reversal
Time-resolved magnetic soft-X-ray spectroscopy We investigate a typical nanometre-scale heterostructure consisting of an amorphous ferrimagnetic Gd25Co75 alloy with…