Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Orange Cats Are Genetically Unlike Any Other Mammal and Now We Know Why
Credit: Pixabay. Chris Kaelin, a geneticist at Stanford Medicine, found himself thinking about cats. Not just any cats,…
Study reveals how a microglial mutation increases risk for Alzheimer’s disease
Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead…
Longevity gene offers hope for children with progeria
A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using…
Pioneering personalized medicine by deciphering depression’s complex biological web
In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that…
Discovery of CPD gene mutations sheds light on rare congenital hearing loss
Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing…
Hotspots of human mutation point to clonal expansions in spermatogonia
Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H.…
Somatic mutation and selection at population scale
Cohort selection The TwinsUK study contains around 16,000 participants. From a preselection of 4,800 donors, we invited 1,796…
“Junk DNA” Provides Surprising New Treatments for Hard-To-Treat Blood Cancers
Researchers at King’s College London have uncovered a surprising vulnerability in certain blood cancers by targeting a part…
Malaria-Transmitting Mosquito’s Genetic Diversity and Evolution Revealed
There are a variety of methods that have been established to curtail the spread of infectious disease, from…