Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers…
New atlas of brain lysosomes sheds light on neurodegenerative disorders
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
Olive oil type matters for cognition and gut health in older adults
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein…
Texture-based analysis of OCT images reveals early retinal changes in diabetes
Diabetic retinopathy (DR) is a leading cause of blindness among working-age adults, affecting more than 130 million people…
Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the…
Fruit flies illuminate the role of Alzheimer’s disease risk genes
Scientists have identified hundreds of genes that may increase the risk of developing Alzheimer’s disease but the roles…
Women with isolated REM sleep behavior disorder show lesser brain atrophy than men
A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson’s disease…
Digital test plus blood biomarker boosts accuracy of Alzheimer’s diagnosis in primary care
By confirming cognitive impairment before ordering amyloid blood tests, this two-step approach cuts false positives, streamlines referrals, and…
Immune-informed brain aging research offers new treatment possibilities, speakers say | MIT News
Understanding how interactions between the central nervous system and the immune system contribute to problems of aging, including…
New TOR inhibitor rapalink-1 prolongs chronological lifespan in fission yeast
Researchers from Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast…