Gut microbiome changes improve memory in early cognitive decline
From Mediterranean diets to probiotics, scientists reveal how reshaping the gut microbiome could help protect brain function, while…
AI Links Brain Rhythms to Physical “Wiring” Across Lifespan
Summary: For the first time, a multinational research team has mapped how the brain’s electrical activity evolves from…
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder
Ayrignac X, Carra-Dalliere C, Codjia P, Mouzat K, Castelnovo G, Ellie E, et al. Evaluation of CSF1R-related adult…
Researchers propose that Parkinson’s disease may start in the gut, not the brain
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal…
Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia
Knopman, D. S. et al. Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021). Article PubMed PubMed Central …
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Aging brains struggle to recycle synaptic proteins
As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren’t sure why. …
Blood gene signals reveal Parkinson’s risk years before diagnosis
Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s diagnosis. Study: Longitudinal assessment of…
Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers…
New atlas of brain lysosomes sheds light on neurodegenerative disorders
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
Olive oil type matters for cognition and gut health in older adults
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…