New study explains how TMEM63B protein regulates cell membranes
An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its inactive…
Shared protein pathology redefines treatment for multiple neurodegenerative diseases
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem…
New study uses sleep monitoring and AI to detect Alzheimer’s
Researchers from Universidad Carlos III de Madrid (UC3M) and Hospital Universitario Severo Ochoa in Leganés, part of the…
Tau buildup in progressive supranuclear palsy alters brain networks linked to thinking and behavior
Researchers at Japan’s National Institutes for Quantum Science and Technology (QST) have found that tau buildup in progressive…
Short sleep and poor sleep quality track with Parkinson’s risk
A large Chinese cohort study suggests that sleep patterns, especially short sleep and poor sleep quality, may help…
Experimental drug shields nerve cells from damage caused by ALS
Amyotrophic Lateral Sclerosis, or ALS, received widespread awareness in the summer of 2014 thanks to an Ice Bucket…
Glucosamine may worsen Alzheimer’s by fueling abnormal brain glycosylation
A widely used joint-health supplement is under scrutiny after researchers linked glucosamine to worsened memory in Alzheimer’s mice…
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
Gladstone investigator wins MIND Prize to decode hidden Alzheimer’s genetics
Gladstone Institutes investigator Ryan Corces, PhD, has been named a 2026 winner of the Pershing Square Foundation’s MIND Prize, a…
Ultraprocessed foods are engineered like cigarettes
If cigarettes were engineered for addiction, are some ultraprocessed foods following the same blueprint? A new analysis reveals…
Neuron lattice structure may guard against neurodegeneration
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
Does motherhood influence brain aging? New research suggests a positive cognitive association
New longitudinal evidence suggests reproductive history may shape women’s cognitive aging, offering insights into possible protective pathways while…