Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases
A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually…
Gladstone investigator wins MIND Prize to decode hidden Alzheimer’s genetics
Gladstone Institutes investigator Ryan Corces, PhD, has been named a 2026 winner of the Pershing Square Foundation’s MIND Prize, a…
Grant supports research into how microglia may spread toxic tau in Alzheimer’s
A researcher with the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio has…
Neuron lattice structure may guard against neurodegeneration
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers…
New atlas of brain lysosomes sheds light on neurodegenerative disorders
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
Minimally invasive biopsy enables real-time tracking of amyloid disease progression
Transthyretin amyloidosis (ATTR) is a rare, progressive and highly aggressive degenerative disease. It is caused by the misfolding…
Regular aerobic exercise slows a key marker of brain aging in midlife
A year of consistent aerobic activity didn’t just boost fitness; it shifted MRI-based brain age in early to…
Prolonged exposure to air pollution linked to elevated risk for ALS
Prolonged exposure to air pollution can be linked to an elevated risk for serious neurodegenerative diseases like ALS…
MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
One of the hallmarks of Alzheimer’s disease is the clumping of proteins called Tau, which form tangled fibrils…
Opposing protein forces fine tune mRNA stability in human cells
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples
Researchers have developed a new tool, FibrilPaint combined with the FibrilRuler test, that allows scientists to directly measure…