More than 400 jobs affected as Mater moves to external pathology providers
Mater has outsourced its pathology services in a move that will affect more than 400 staff. The announcement…
Oncogenic mutations in non-small cell lung cancer: from molecular mechanisms to clinical practice
Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers…
Could the Mediterranean diet protect the brain through the gut?
From microbial metabolites to inflammation and the blood-brain barrier, researchers trace how Mediterranean eating could influence neurodegeneration, while…
Active form of meprin-β protein increases in people with Alzheimer’s disease
A team from the Altered Molecular Mechanism in Alzheimer’s Disease and Dementia laboratory, led by Javier Sáez Valero,…
Itaconate and its derivatives in human health and diseases
Wu, R. et al. ACOD1 in immunometabolism and disease. Cell Mol. Immunol. 17, 822–833 (2020). Article CAS PubMed …
Faulty myelin-making brain cells may help drive cognitive decline with age
A rare combination of lifelong cognitive tracking, postmortem brain analysis, and targeted mouse experiments reveals unexpected changes in…
Shared protein pathology redefines treatment for multiple neurodegenerative diseases
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem…
Lancet review examines possible amyloid-beta transmission through blood transfusions
A review and opinion piece published in The Lancet and led by UCL (University College London) and UCLH…
Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes
From mitochondrial fragmentation to antioxidant defenses, researchers reveal how the same viruses can drive cellular damage in vertebrates…
AI-based methods help uncover hidden roots of tumor metastasis
A cancerous tumor is not a single enemy. It is made up of many different cell populations that…
A closer look at Parkinson’s brains finds tau where standard tests saw little
By examining six brain regions at single-molecule resolution, researchers identified a layer of tau pathology that conventional tissue…
RNA-based testing can improve detection of key lung cancer biomarkers
New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations…