Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
Remote-controlled CAR T cells offer safer cancer therapy
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
University of Missouri launches first on-campus radiopharmaceutical clinical trial
In a major leap for cancer care at the University of Missouri, the School of Medicine and MU…
Tumor-targeted chimeric drug increases efficacy and limits side effects
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
Immune scaffold predicts onset weeks early
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
Hippocampus reorganizes memories to anticipate future outcomes, study finds
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
Olive oil type matters for cognition and gut health in older adults
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
Preclinical study reveals potential new treatment for severe liver fibrosis
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…