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Browsing Tag

Preclinical

33 posts
SScience
Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials
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Hippocampus reorganizes memories to anticipate future outcomes, study finds

  • January 30, 2026
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
HHealth
Study: Total and different types of olive oil consumption, gut microbiota, and cognitive function changes in older adults. Image Credit: Mehes Daniel / Shutterstock
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Olive oil type matters for cognition and gut health in older adults

  • January 27, 2026
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…
SScience
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
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Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

  • January 27, 2026
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
HHealth
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
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Preclinical study reveals potential new treatment for severe liver fibrosis

  • January 14, 2026
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
HHealth
New insights reveal persistent genome structure during cell division
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Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

  • December 30, 2025
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
HHealth
Regular mammograms linked to longer survival in women over 80
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Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

  • December 27, 2025
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
HHealth
Simple blood test maps hidden Alzheimer’s disease changes
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Simple blood test maps hidden Alzheimer’s disease changes

  • December 21, 2025
A large community study shows that Alzheimer’s-related brain changes are far more widespread with age than symptoms alone…
HHealth
New imaging technique enhances live-cell visualization in standard lab setups
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UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington’s disease

  • December 13, 2025
Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at…
SScience
New technology embeds unique genetic identifiers in engineered cells
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Most clinical trials fail to reflect America’s racial and ethnic diversity

  • December 12, 2025
A new study finds just 6% of clinical trials used to approve new drugs in the U.S. reflect…
HHealth
Study: Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses. Image Credit: Corona Borealis Studio / Shutterstock
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Dietary restriction boosts antitumour immunity by rewiring T cell metabolism

  • December 11, 2025
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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WSU researchers discover how a neural circuit drives relapse after opioid use

  • December 9, 2025
Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions…
HHealth
Regular mammograms linked to longer survival in women over 80
Read More

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

  • December 5, 2025
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
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