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Browsing Tag

Preclinical

48 posts
HHealth
Blood markers can indicate people at risk of developing ulcerative colitis
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EV-RNAs show promise for IBD diagnosis and treatment

  • April 11, 2026
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…
TTechnology
Targeted diet helps reprogram aggressive neuroblastoma in mice
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Targeted diet helps reprogram aggressive neuroblastoma in mice

  • April 10, 2026
A new commentary spotlights preclinical evidence that blocking key amino acids, along with a polyamine-blocking drug, may force…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

  • April 6, 2026
Mayo Clinic researchers developed an experimental nanotherapy that delivers two cancer drugs directly to brain tumors, according to…
TTechnology
Study: In vivo metabolic tagging and targeting of circulating red blood cells. Image Credit: The1969 Studio / Shutterstock
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Scientists turn red blood cells into long-lasting drug and imaging carriers in mice

  • March 24, 2026
A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting…
HHealth
Study shows record surge in reduced kidney function worldwide
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New strategy to fight chronic kidney inflammation

  • March 10, 2026
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent…
HHealth
Study: Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study. Image Credit: Kotcha K / Shutterstock
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Could GLP-1 drugs help curb addiction? Large veteran study points to potential benefit

  • March 9, 2026
A major study of US veterans suggests that GLP-1 diabetes medications may influence addiction-related outcomes, revealing a surprising…
HHealth
New research initiative aims to predict and prevent diseases before they start
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New research initiative aims to predict and prevent diseases before they start

  • March 2, 2026
What if doctors could tell you a disease was coming years before you felt a single symptom-and stop…
HHealth
Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock
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How zinc deficiency could worsen heart inflammation and what that means for patients

  • March 2, 2026
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence…
HHealth
Study: Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease. Image Credit: MP Art / Shutterstock
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Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s

  • February 27, 2026
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
HHealth
Study: Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease
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Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

  • February 23, 2026
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
TTechnology
New microfluidic-based biosensing platform helps track live antibody secretion dynamics
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Remote-controlled CAR T cells offer safer cancer therapy

  • February 20, 2026
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells…
HHealth
Study: Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease. Image Credit: Andrii Vodolazhskyi / Shutterstock
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

  • February 12, 2026
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
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