Targeted antibody therapy provides long-lasting relief from neuropathic pain
Pain is a natural protective mechanism that alerts the body to actual or potential injury. But when nerves…
Early studies hint that ketones may affect pathways linked to PTSD
From altered brain energy metabolism to inflammation and neurotransmitter signaling, researchers examine why raising ketone levels has drawn…
Inhibitory neurons act as a brake on brain tumor growth
Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where…
Psilocybin protects sensory nerves from chemotherapy damage in preclinical study
From mouse models to freshly isolated human nerves, researchers traced what happens when chemotherapy disrupts the cellular machinery…
Targeting KV7 proteins could help delay preterm labor
Scientists have found that targeting a particular group of proteins in the uterus muscle (myometrium) can suppress human…
From caffeine to trigonelline, coffee has surprising links to muscle biology
From NAD+ metabolism and glucose uptake to muscle mass and frailty, researchers mapped how coffee and its compounds…
Colorectal tumors may damage nerves before chemotherapy
Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer,…
Childhood trauma affects brain pathways linked to adult anhedonia
Experiencing trauma in childhood can lead to a lack of motivation and less pleasure from rewards-or anhedonia-later in…
Why pulses could play a bigger role in healthy and sustainable diets
From feeding beneficial gut microbes to improving selected metabolic markers, pulses combine nutrient density with sustainability, but researchers…
New injectable hydrogel accelerates healing of deep wounds
Any minor cut or scrape sets the body’s natural healing process in motion. However, deep wounds are far…
Amyloid beta misfolding predicts Alzheimer’s years before symptoms appear
Widely used Alzheimer’s biomarker P-tau 217 reliably detects the disease only at the clinical stage. The protein misfolding…
New mechanism behind chemotherapy resistance in ovarian cancer discovered
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer…