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Browsing Tag

Preclinical

87 posts
SScience
Human telomerase shows limited function across different animal species
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Human telomerase shows limited function across different animal species

  • May 6, 2026
A new research paper was published in Volume 18 of Aging-US on April 13, 2026, titled “Cross species activity of TERT…
HHealth
Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials
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Scientists identify STING switch driving inflammation in Alzheimer’s disease

  • April 25, 2026
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
HHealth
New insights reveal persistent genome structure during cell division
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Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models

  • April 23, 2026
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…
HHealth
Blood markers can indicate people at risk of developing ulcerative colitis
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EV-RNAs show promise for IBD diagnosis and treatment

  • April 11, 2026
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…
TTechnology
Targeted diet helps reprogram aggressive neuroblastoma in mice
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Targeted diet helps reprogram aggressive neuroblastoma in mice

  • April 10, 2026
A new commentary spotlights preclinical evidence that blocking key amino acids, along with a polyamine-blocking drug, may force…
HHealth
Mapping the evolutionary trajectory of meningiomas at single-cell resolution
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Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

  • April 6, 2026
Mayo Clinic researchers developed an experimental nanotherapy that delivers two cancer drugs directly to brain tumors, according to…
TTechnology
Study: In vivo metabolic tagging and targeting of circulating red blood cells. Image Credit: The1969 Studio / Shutterstock
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Scientists turn red blood cells into long-lasting drug and imaging carriers in mice

  • March 24, 2026
A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting…
HHealth
Study shows record surge in reduced kidney function worldwide
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New strategy to fight chronic kidney inflammation

  • March 10, 2026
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent…
HHealth
Study: Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study. Image Credit: Kotcha K / Shutterstock
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Could GLP-1 drugs help curb addiction? Large veteran study points to potential benefit

  • March 9, 2026
A major study of US veterans suggests that GLP-1 diabetes medications may influence addiction-related outcomes, revealing a surprising…
HHealth
New research initiative aims to predict and prevent diseases before they start
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New research initiative aims to predict and prevent diseases before they start

  • March 2, 2026
What if doctors could tell you a disease was coming years before you felt a single symptom-and stop…
HHealth
Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock
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How zinc deficiency could worsen heart inflammation and what that means for patients

  • March 2, 2026
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence…
HHealth
Study: Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease. Image Credit: MP Art / Shutterstock
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Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s

  • February 27, 2026
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
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