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Browsing Tag

Preclinical

87 posts
HHealth
Resistance exercise may offer greater benefits for preventing diabetes and obesity
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Resistance exercise may offer greater benefits for preventing diabetes and obesity

  • November 4, 2025
Running may help burn calories, but when it comes to preventing diabetes and obesity, pumping iron might have…
TTechnology
Novel treatment disrupts tumor immunosuppression in pancreatic cancer
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Northwestern team develops antibody to expose hidden pancreatic cancer cells

  • November 4, 2025
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
HHealth
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
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Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

  • November 1, 2025
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
SScience
Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance
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Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

  • October 30, 2025
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

  • October 30, 2025
A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and…
HHealth
Study: SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade. Image Credit: KwangSoo Kim / Shutterstock
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How COVID mRNA vaccines may make cancer treatments more effective

  • October 24, 2025
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
HHealth
Georgia State scientist receives $25,000 grant to develop mechanisms for treating obesity
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Strong grip strength lowers risk of organ dysfunction in obesity

  • October 21, 2025
People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Engineered Salmonella therapy delivers immune payloads to combat cancer

  • October 8, 2025
A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled “ACTM-838, a novel systemically delivered…
HHealth
Researchers identify a central controller of mitochondrial dynamics in disease
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Researchers identify a central controller of mitochondrial dynamics in disease

  • October 6, 2025
A key switch for cellular energy balance has been discovered in cells: it could potentially become the target…
HHealth
New technology embeds unique genetic identifiers in engineered cells
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Highly targeted gene therapy could revolutionize treatment for cancers linked to herpesvirus

  • October 3, 2025
In a preclinical study, UC Davis Comprehensive Cancer Center scientists developed a highly targeted gene therapy that could…
HHealth
Mapping the dynamics of complex protein
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Mapping the dynamics of complex protein

  • October 2, 2025
Discover how the University of Manchester was able to explore the dynamics of complex proteins thanks to Bruker’s groundbreaking…
GGenetics
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Genetic modification enhances “living drugs” for blood cancers

  • September 25, 2025
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…
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