Reframing the role of MCL1 in cancer signaling and metabolism
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…