Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Kiwifruit intake boosts vitamin C in skin and supports dermal structure
By directly measuring vitamin C inside human skin, researchers show that diet can boost skin vitamin C content…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Lab-grown organoid offers a platform to study how liver scarring develops
As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates…
Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
Drinking soft drinks may fuel depression by altering gut bacteria
Researchers have uncovered a surprising link between everyday soft drink habits and mental health, revealing that even moderate…
Study provides new insights into the mechanisms of fetal membrane healing
When a pregnant woman’s water breaks too early, it often leads to preterm birth, with no effective method…
Study reveals a new oncogenic role of NBL1 in ovarian cancer metastasis
Ovarian cancer (OC), one of the three most common gynecological malignancies, is characterized by low early detection rates…
Study identifies C1orf122 as prognostic marker in liver cancer
Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for…