Intercellular heme transfer pathway sustains red blood cell production under stress
Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they…
Scientists identify STING switch driving inflammation in Alzheimer’s disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
Exploiting a new weakness in ‘zombie-like’ cells to treat senescence-associated diseases
A new set of drugs exploit a recently-revealed weakness in ‘zombie-like’ – or senescent – cells that could lead to new treatments for cancer and age-associated diseases. The study from the…
Study reframes Hodgkin lymphoma as a cancer of failed cell development
For the first time, Weill Cornell Medicine researchers have demonstrated that Hodgkin lymphoma cancer cells from patient samples…
L-arginine stabilizes protein droplets and prevents harmful fibril formation
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns
A newly characterized bat coronavirus can latch onto a human cell receptor found in the lung, giving scientists…
High levels of gut bacterial toxin linked to increased lupus nephritis risk
The body’s immune reaction to increased levels of a toxic molecule, part of a bacterial species in the…
Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…
Blood protein levels shift significantly from childhood through early adulthood
Blood protein levels change markedly already during childhood and adolescence, and differences between girls and boys become increasingly…
New molecule weakens glioblastoma and enhances immune response
A team of researchers from Brown University Health and Brown University has uncovered an important clue in the…
Epigenome proteins shape dynamic gene expression beyond simple on-off
A new study finds the proteins responsible for controlling which genes are expressed in a genome do more…
United States Meat Market: Steady as a Rock Protein Powerhouse
The United States Meat Market continues to be one of the most important and most productive segments of…