Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
Review links betel nut addiction to cancer, heart disease, and metabolic risks
Widely used yet often underestimated, betel nut chewing poses significant health risks, and researchers continue to search for…
Estrogen levels in the brain may play a role in women’s risk of stress-related memory problems
Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting…
Bacteria repurpose viral injection systems to target diverse cells
New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types…
Palbociclib improves progression-free survival in HER2 positive breast cancer
PrECOG, LLC, today announced the publication of final results from the pivotal phase 3 PATINA study in the…
Research uncovers alternative inflammatory pathway in rheumatoid arthritis treatment
The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but…
Targeted Fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
Incretin-based diabetes drugs show potential protective effects against dementia
A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes,…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…