Research uncovers alternative inflammatory pathway in rheumatoid arthritis treatment
The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but…
Targeted Fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
Incretin-based diabetes drugs show potential protective effects against dementia
A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes,…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…
Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
Blocking platelet-activating factor reduces liver damage in cirrhosis
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural…
Cryo-EM reveals NPFFR1 activation and guides novel ligand design
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1…
Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch
A microbial metabolite long linked to cardiovascular risk emerges as a surprising ally against metabolic inflammation, revealing how…
WSU researchers discover how a neural circuit drives relapse after opioid use
Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions…
Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease
A phase 2 trial suggests that a drug commonly used for constipation may help preserve kidney function in…
Study shines light on how P2X4 receptor can be inhibited
A study carried out by the University of Bonn and the University Hospital Bonn throws light on how…