Study reveals insights into how cells coordinate gene compensation response
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or…
Engineered enzyme enables fast and accurate RNA synthesis
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Immune scaffold predicts onset weeks early
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
Novel RNA molecule may influence patient survival in certain blood cancers
In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health…
New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
Dynamic viral markers predict treatment response in hepatitis B
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…
Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers…
Short-term oatmeal diet improves cholesterol and metabolic health markers
A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by…
Targeted uterine mRNA treatment boosts fertility outcomes in mice
Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine – which designs nanotechnology-based platforms for…
Sperm RNA aging shift that may explain paternal age effects
A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life,…