Spaceflight research opens new avenues for studying rare pediatric diseases
Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis…
New mathematical method maps gene roles across different species
Background Much of what we know about biology comes from animal models, particularly mice. Applying these insights to…
Ancient viral DNA offers clues to why human and chimpanzee brains evolved differently
An ancient viral insertion silences LINC00662 in chimpanzee cells, while the gene is active during early human brain…
AI Can Detect Hidden Signs of Aging in the 3D Architecture of DNA
A new AI tool can read hidden signatures of aging from ordinary microscopy images of blood-forming stem cells.…
Human Embryo Models Show Important Biological Differences
For decades, scientists have dreamed of peering into the earliest days of human life, those fragile moments when…
Active form of meprin-β protein increases in people with Alzheimer’s disease
A team from the Altered Molecular Mechanism in Alzheimer’s Disease and Dementia laboratory, led by Javier Sáez Valero,…
Norwegian scientists harvest super donor cells to fight diverse diseases
Cells from nine “super donors” are being collected in Oslo. The aim is for these to be used…
Study uncovers how interferon-alpha treats rare blood cancers
The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem…
Crucial brain stem cells rely on metabolic pathways to make decisions
As the human brain takes shape before birth, a remarkable type of stem cell helps give it many…
Chinese stem cell therapy reverses heart failure in 90% of patients, landmark trial finds
A groundbreaking stem cell therapy could reverse severe heart failure in 90 per cent of patients in a…
Researchers maintain brain organoids for longer than ever before
An international team of researchers has maintained brain organoids, three-dimensional models of human brain tissue, for longer than…
Penn State team lays groundwork to 3D print spheroids for regenerating bone tissue
An interdisciplinary team of engineers and chemists at Penn State has laid the groundwork to 3D print spheroids…